Yes go in September
Be prepared for cool weather, but the aspen will be turning. We were there last week. We stayed in Cody at Absaroka Bay. It is a pretty drive of an hour to east entrance. You can also (without trailer) go over Chief Joseph Scenic hiway up to Cooke City (NE entrance) which drops you into Lamar Valley which has buffalo, pronghorn, Deer. Be aware that road from Canyon to Tower is closed, so plan loop drives accordingly
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