We travel 54 - a lot of two lane, I'll say truck traffic is light to moderate. We normally leave Manhattan KS with a full tank, fill up again in Guymon OK and that gets us to Tucumcari with good reserves. Not retired yet so we do the 'we gotta do it in one day' thing so can't give any advice on where to stay but be aware, there are no rest stops so bring your own
. Best wishes and stay safe.