Remember that the weapon has it's own shot to shot repeat-ability tolerance so at some point you will need to fire a group to determine it's overall accuracy. Since it's a new rifle I think I would do it early on. That way you won't be chasing 2" when the weapon is only capable of 3".
Probably the best time is at the verification, when the aiming point and the hole are pretty close try 2 more to get a 3 round group. It will almost certainly take several sets of groups before you are really comfortable [satisfied] with the settings.