Welcome to the forum!
Actually you're not pulling with an F250 vs anybody elses F350, you're pulling with whatever drive train you keep under the hood and floorboards of that Ford combined with the gear ration, and they are pretty much the same in both trucks.
What you are doing that you should be concerned about is dropping about 2.400 to 2,800 lbs of pin weight in addition to you and your other half and whatevery cargo you carry into an F250 that probably doesn't have the payload rating to carry it.
But I suspect you already knew that.
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