For a newer truck that may be great. With both my previous '02 Chevy (8.1L gasser w/Allison tranny) and current '06 Ford (diesel) I don't use it save for either extreme uphill or downhill grades (gain a bit of engine braking). It just works the engine too much for regular towing and kills mileage without really helping anything.
We're completing our 8,700 mile trip from VA through WV, KY to Omaha, then to Denver, Ogden, Carson City, Fresno, San Francisco, Reno and straight back east. Only used tow/haul on steep downhill grades the entire trip. Did use 4 wheel drive on a couple of steep uphill gravel roads though.
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